Toxicology – Københavns Universitet

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AEM > Kurser > Toxicology

Applied Toxicology

Week 3-5, 2017

Learning objectives

A student who has met the objectives of the course will be able to:


  1. Know about various areas of regulation of chemicals
  2. Know about guideline methods


  1. Assess toxicological studies for quality and reliability
  2. Perform a risk assessment
  3. Perform a toxicological necropsy


The Department of Experimental Medicine at the University of Copenhagen, in collaboration with the Technical University of Denmark, offer a postgraduate course in applied toxicology. The focus of the course is on risk assessment of chemical substances. The purpose of the course is to provide a background for work with toxicological risk assessment. Toxicological risk assessments are performed in many areas of regulation, e.g. in the setting of occupational exposure limits, health-based quality criteria for environmental pollutants and toxicological reference values for chemical substances that can be found in food (contaminants, pesticides, food additives, in relation to assessment of cosmetics, and in the preparation or assessment of toxicological evaluations from producers of chemicals or pharmaceuticals. 

The various steps in the risk assessment process are presented: Hazard identification and characterisation, exposure assessment and risk characterisation. Relevant international organisations and risk assessment programmes, the individual toxicological endpoints and their test methods and guidance documents, and data retrieval are included.

Specific content is: Toxicological endpoints and guidelines (toxicokinetics, acute toxicity, local irritation, sensitisation, repeated dose toxicity, mutagenicity/genotoxicity, carcinogenicity, toxicity to reproduction and developmental toxicity); elements of guideline studies (necropsy, haematology, clinical chemistry); practical advice (study planning, how to find data).


Ph.d.-students and veterinarians, MDs, pharmacists and other persons with a biomedical academic background. 




The course contains theoretical lectures and practical exercises, including a visit to a toxicological test laboratory, a practical exercise in necropsy technique, and homework. The course concludes with a written examination.

Course director

Klas Abelson; Associate Professor, PhD; Department of Experimental Medicine;


Grete Østergaard, Department of Experimental Medicine, University of Copenhagen
Elsa Nielsen, DTU National Food Institute
Charlotte Madsen, DTU National Food Institute
Anoop Kumar Sharma, DTU National Food Institute
Alicja Mortensen, DTU National Food Institute
Sofie Christiansen, DTU National Food Institute
Trine Reffstrup, DTU National Food Institute
Camilla Taxvig, DTU National Food Institute
Eva Bay Wedebye, DTU National Food Institute
Karin Sørig Hougaard, National Research Center for Working Environment
Henrik Tang Vestergaard, H. Lundbeck A/S
Sidsel Dyekjær, Danish Environmental Protection Agency
Trine Thorup Andersen, Danish Environmental Protection Agency
Maria Schlippe Jakobsen, CiToxLAB Scantox

Course secretary

Gitte Kaltoft Nielsen (


January 16 - February 2, 2017

Course location

Department of Experimental , Panum Building, Blegdamsvej 3B, DK-2200 Copenhagen N

Registration and price

Click link for registration: Link to registration form