Phenotyping of Genetically Engineered Mouse Models

Aim and content

The aim of the course is to teach and train the participants in approaches to efficient phenotyping of genetically engineered mouse models, and provide a deeper understanding of possibilities and limitations in the translation from findings in mouse models to relevance for human diseases.

The course consists of lectures on various genetically engineered mouse models and phenotypic evaluation of these with a special focus on pathology; seminars and group work with critical review of translational research; and practical exercises in phenotyping and pathological evaluation of mice.

Learning objectives

A student who has met the objectives of the course will be able to:

  • Describe different approaches to phenotyping of genetically engineered mouse model (knowledge)
  • Analyse and reflect on pitfalls in induction of genetically engineered mouse models (skills)
  • Understand and evaluate possibilities and limitations in the translation from findings in mouse models to relevance for human diseases (skills)
  • Have insight in how to perform necropsy and histopathological analysis in mice (knowledge)

Participants

PhD students who are using, or are about to start using, genetically engineered mice in their research. It is mandatory that participants have passed a course equivalent to Laboratory Animal Science, EU function AD or ABD.

Language

English.

Form
Lectures, seminars, panel discussions, group-work, and hands-on practicals with animals.

Course directors

Dr. Klas Abelson, Professor, PhD
Department of Experimental Medicine, University of Copenhagen.

Teachers

Dr. Cory Brayton, Associate Professor at the Department of Molecular and Comparative Pathobiology and Phenotyping Core Center at Johns Hopkins University School of Medicine, Baltimore, MD, USA

Cord Brakebusch, Professor,

Dr. Klas Abelson, Professor, PhD

Time

Autumn 2025

Place

The Panum Building, Blegdamsvej 3, DK-2200 Copenhagen N

Registration and price

Click here for registration