Department of Experimental Medicine

  1. 2019
  2. Published

    Clinical, Physiologic, and Behavioral Evaluation of Permanently Catheterized NMRI Mice

    Falkenberg, M. K., Teilmann, A. C., Henriksen, T., Hau, Jann, Poulsen, Henrik Enghusen & Abelson, Klas, 1 May 2019, In: Journal of the American Association for Laboratory Animal Science : JAALAS. 58, 3, p. 380-389

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Relationships between captive chimpanzee (Pan troglodytes) welfare and voluntary participation in behavioural studies

    Neal Webb, S. J., Hau, Jann & Schapiro, S. J., 1 May 2019, In: Applied Animal Behaviour Science. 214, p. 102-109

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Time-dependent Pathologic and Inflammatory Consequences of Various Blood Sampling Techniques in Mice

    Sørensen, Dorte Bratbo, Metzdorff, S. B., Jensen, Louise Kruse, Andersen, K. H., Teilmann, A. C., Jensen, Henrik Elvang & Frøkiær, Hanne, May 2019, In: JAALAS - Journal of the American Association for Laboratory Animal Science. 58, 3, p. 362-372

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Granulovacuolar Degeneration in Brains of Senile Cynomolgus Monkeys

    Darusman, H. S., Agungpriyono, D. R., Kusumaputri, V. A., Sajuthi, D., Schapiro, S. J. & Hau, Jann, 7 Mar 2019, In: Frontiers in Aging Neuroscience. 11, p. 1-5 50.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    The analgesic efficacy of morphine varies with rat strain and experimental pain model: implications for target validation efforts in pain drug discovery

    Hestehave, Sara, Abelson, Klas, Brønnum Pedersen, T. & Munro, G., Mar 2019, In: European Journal of Pain (United Kingdom). 23, 3, p. 539-554 16 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Chimpanzees Rarely Settle on Consistent Patterns of Play in the Hawk Dove, Assurance, and Prisoner's Dilemma Games, in a Token Exchange Task

    Hall, K., Smith, M., Russell, J. L., Lambeth, S. P., Schapiro, S. J. & Brosnan, S. F., Feb 2019, In: Animal behavior and cognition. 6, 1, p. 48-70

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Does group size matter? Captive chimpanzee (Pan troglodytes) behavior as a function of group size and composition

    Webb, S. J. N., Hau, Jann & Schapiro, S. J., Jan 2019, In: American Journal of Primatology. 81, 1, p. 42-51 e22947.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Behavioral conservatism is linked to complexity of behavior in chimpanzees (Pan troglodytes): Implications for cognition and cumulative culture

    SJ, D., Schapiro, S., Lambeth, S., Wood, L. & Whiten, A., 2019, In: Journal of Comparative Psychology. 133, 1, p. 20-35

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Failure to replicate? Exacerbated 8-OH-DPAT-induced hypothermia could not be established in single housed mice when tested as part of a battery of depression tests

    Skriver, H., Kjær, M. R., Sørensen, Dorte Bratbo & Kalliokoski, Otto, 2019, In: Scandinavian Journal of Laboratory Animal Science. 45, p. 1-11 11 p., 4.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Markers of HPA-axis activity and nucleic acid damage from oxidation after electroconvulsive stimulations in rats

    Jørgensen, Anders, Breitenstein, K., Kalliokoski, Otto, Weimann, A., Henriksen, T., Poulsen, Henrik Enghusen, Jørgensen, Martin Balslev & Wörtwein, Gitta, 2019, In: Acta Neuropsychiatrica. 31, 6, p. 287-293 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. 2018
  13. Published

    A COMPARISON OF ACTIVITY PATTERNS OF CAPTIVE CHIMPANZEES (PAN TROGLODYTES) HOUSED IN PRIMADOMES™ OR CORRALS

    Webb, S. J. N., Hau, Jann & Schapiro, S. J., Dec 2018, In: American Journal of Primatology. 80, S1, p. 45-46 141.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  14. Published

    Refinements to captive chimpanzee (Pan troglodytes) care: A selfmedication paradigm

    Webb, S. J. N., Hau, Jann & Schapiro, S. J., 1 Nov 2018, In: Animal Welfare. 27, 4, p. 327-341 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Chimpanzees demonstrate individual differences in social information use

    Watson, S. K., Vale, G. L., Hopper, L., Dean, L., Kendal, R. L., Price, E., Wood, L., SJ, D., Schapiro, S., Lambeth, S. & Whiten, A., Sep 2018, In: Animal Cognition. 21, 5, p. 639-650

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Are we overestimating the utility of hair glucocorticoids? A systematic review exploring the empirical evidence supporting hair glucocorticoids as a measure of stress

    Kalliokoski, Otto, Jellestad, F. K. & Murison, R., 24 Jul 2018, In: bioRxiv. 375667.

    Research output: Contribution to journalJournal articleResearch

  17. Published

    Neuroanatomical Correlates of Hierarchical Personality Traits in Chimpanzees: Associations with Limbic Structures

    Latzman, R. D., Boysen, S. T. & Schapiro, S., 17 Jul 2018, In: Personality Neuroscience. 1, 11 p., e4.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Transdermal Fentanyl Solution Provides Long-term Analgesia in the Hind-paw Incisional Model of Postoperative Pain in Male Rats

    Clemensen, J., Rasmussen, L. V. & Abelson, Klas, 1 Jul 2018, In: In Vivo. 32, 4, p. 713-719 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Angiogenesis PET Tracer Uptake (68Ga-NODAGA-E[(cRGDyK)]2) in Induced Myocardial Infarction and Stromal Cell Treatment in Minipigs

    Rasmussen, T., Follin, B., Kastrup, J., Brandt-Larsen, M., Madsen, J., Christensen, T. E., Juhl, M., Cohen, S., Hammelev, Karsten Pharao, Møller, Christian H., Goetze, Jens P. , Hasbak, P. & Kjær, Andreas, Jun 2018, In: Diagnostics. 8, 2, p. 1-12 33.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Chimpanzees prioritise social information over pre-existing behaviours in a group context but not in dyads

    Watson, S. K., Lambeth, S. P., Schapiro, S. J. & Whiten, A., 1 May 2018, In: Animal Cognition. 21, 3, p. 407-418 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Single-Dose Bone Pharmacokinetics of Vancomycin in a Porcine Implant-Associated Osteomyelitis Model

    Bue, M., Hanberg, P., Koch, J., Jensen, Louise Kruse, Lundorff, M., Aalbæk, Bent, Jensen, Henrik Elvang, Søballe, K. & Tøttrup, M., Apr 2018, In: Journal of Orthopaedic Research. 36, 4, p. 1093-1098

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Captive chimpanzee (Pan troglodytes) behavior as a function of space per animal and enclosure type

    Neal Webb, S. J., Hau, Jann & Schapiro, S. J., 1 Mar 2018, In: American Journal of Primatology. 80, 3, 9 p., e22749.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Diurnal rhythms of blood glucose, serum ghrelin, faecal IgA and faecal corticosterone in rats subjected to restricted feeding using the diet board

    Kasanen, I., Inhilä, K., Savontaus, E., Voipio, H., Õkva, K., Mering, S., Kiviniemi, V., Hau, Jann, Laaksonen, S. & Nevalainen, T., 1 Feb 2018, In: Laboratory Animals. 52, 1, p. 29-37

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Ultrasonographic and histological evaluation of the effects of long-term carotid catheterization on cardiac function in NMRI mice

    Teilmann, A. C., Thomsen, Morten Bækgaard, Ihms, E. A., Pate, N., Hau, Jann & Abelson, Klas, Feb 2018, In: Laboratory Animals. 52, 1, p. 17-28

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    A comparison of various methods of blood sampling in mice and rats: Effects on animal welfare

    Sreelatha, Harikrishnan Vijayakumar, Hansen, Axel Kornerup, Abelson, Klas & Sørensen, Dorte Bratbo, 2018, In: Laboratory Animals. 52, 3, p. 253-264

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    A new genetic tool to improve immune-compromised mouse models: Derivation and CRISPR/Cas9-mediated targeting of NRG embryonic stem cell lines

    Martin Gonzalez, Javier, Baudet, A., Abelechian, Sahar, Bonderup, K., d'Altri, T., Porse, Bo Torben, Brakebusch, Cord Herbert, Juliusson, G. & Cammenga, J., 2018, In: Genesis: The Journal of Genetics and Development (Print). 56, 9, p. 1-7 7 p., e23238.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    Anaesthesia, Analgesia, and Euthanasia

    Abelson, Klas, 2018, Laboratory Animal Science: A handbook on experimental animals and animal experimentation. Bratbo Sørensen, D. (ed.). Copenhagen: University of Copenhagen, p. 71-95

    Research output: Chapter in Book/Report/Conference proceedingBook chapterEducationpeer-review

  28. Published

    Animal Experimentation in Africa: Legislation and Guidelines: Prospects for Continued Progress

    Hau, A., Guhad, F. A., Cooper, M., Farah, I. O., Mohr, B. J., Souilem, O. & Hau, Jann, 2018, Laboratory Animals: Regulations and Recommendations for the Care and Use of Animals in Research. Guillén, J. (ed.). 2 ed. Elsevier, p. 221–236

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearch

  29. Published

    Classification and reporting of severity experienced by animals used in scientific procedures: FELASA/ECLAM/ESLAV Working Group report

    Smith, D., Anderson, D., Degryse, A., Bol, C., Criado, A., Ferrara, A., Franco, N. H., Gyertyan, I., Orellana, J. M., Østergaard, Grete, Varga, O. & Voipio, H., 2018, In: Laboratory Animals. 52, 1_suppl, p. 5-57

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Published

    Epigenetic control of IL-23 expression in keratinocytes is important for chronic skin inflammation

    Li, H., Yao, Q., Mariscal, A. G., Wu, X., Hülse, J., Pedersen, E., Helin, K., Waisman, A., Vinkel, C., Thomsen, Simon Francis, Avgustinova, A., Benitah, S. A., Lovato, P., Norsgaard, H., Mortensen, M. S., Veng, L., Rozell, B. & Brakebusch, Cord Herbert, 2018, In: Nature Communications. 9, 1, p. 1-18 18 p., 1420.

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. Published

    Handling, Husbandry, and the Use of Research Animals

    Abelson, Klas, Krohn, T. C. & Østergaard, Grete, 2018, Laboratory Animal Science: A handbook on experimental animals and animal experimentation. Bratbo Sørensen, D. (ed.). Copenhagen: University of Copenhagen, p. 37-69

    Research output: Chapter in Book/Report/Conference proceedingBook chapterEducationpeer-review

  32. Published

    Loss of PICH Results in Chromosomal Instability, p53 Activation, and Embryonic Lethality

    Albers, E., Sbroggiò, M., Pladevall Morera, David, Bizard, A. H., Avram, Alexandra Ioana, Gonzalez, P., Martin Gonzalez, Javier, Hickson, Ian David & Lopez-Contreras, Andres, 2018, In: Cell Reports. 24, 12, p. 3274-3284 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. Published

    Softened food reduces weight loss in the streptozotocin-induced male mouse model of diabetic nephropathy

    Nørgaard, S. A., Sand, F. W., Sørensen, Dorte Bratbo, Abelson, Klas & Søndergaard, H., 2018, In: Laboratory Animals. 52, 4, p. 373-383

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. 2017
  35. Published

    Effects of transportation, relocation, and acclimation on phenotypes and functional characteristics of peripheral blood lymphocytes in rhesus monkeys (Macaca mulatta)

    Nehete, P. N., Shelton, K. A., Nehete, B. P., Chitta, S., Williams, L. E., Schapiro, S. J. & Abee, C. R., 19 Dec 2017, In: PLOS ONE. 12, 12, 15 p., e0188694.

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. Published

    Is there a reasonable excuse for not providing post-operative analgesia when using animal models of peripheral neuropathic pain for research purposes?

    Hestehave, Sara, Munro, G., Christensen, R., Brønnum Pedersen, T., Arvastson, L., Hougaard, P. & Abelson, Klas, 22 Nov 2017, In: PloS one. 12, 11, p. 1-23 e0188113.

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. Published

    Modulation of formalin-induced pain-related behaviour by clonidine and yohimbine in the Speke's hinged tortoise (Kiniskys spekii)

    Makau, C. M., Towett, P. K., Abelson, Klas & Kanui, T. I., Oct 2017, In: Journal of Veterinary Pharmacology and Therapeutics. 40, 5, p. 439–446

    Research output: Contribution to journalJournal articleResearchpeer-review

  38. Published

    Behaviour, stress and welfare of Sprague Dawley rats (Rattus norvegicus) on diet board feeding for 24 months

    Laaksonen, S., Nevalainen, T., Ketola, J., Hau, Jann, Nieminen, P., Haasio, K., Kasanen, I. & Voipio, H. M., Sep 2017, In: Applied Animal Behaviour Science. 194, p. 86-94 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. Published

    Triarchic Psychopathy Dimensions in Chimpanzees (Pan troglodytes): Investigating Associations with Genetic Variation in the Vasopressin Receptor 1A Gene

    Latzman, R. D., Schapiro, S. J. & Hopkins, W. D., 17 Jul 2017, In: Frontiers in Neuroscience. 11, JUL, 10 p., 407.

    Research output: Contribution to journalJournal articleResearchpeer-review

  40. Published

    Four simple rules that are sufficient to generate the mammalian blastocyst

    Nissen, Silas Boye, Perera Pérez, Marta, Martin Gonzalez, Javier, Morgani, S. M. C., Jensen, Mogens Høgh, Sneppen, Kim, Brickman, Joshua Mark & Trusina, Ala, 12 Jul 2017, In: PLOS Biology. 15, 7, p. 1-30 e2000737.

    Research output: Contribution to journalJournal articleResearchpeer-review

  41. Published

    A simple DNA recombination screening method by RT-PCR as an alternative to Southern blot

    Albers, E., Sbroggiò, M., Martin Gonzalez, Javier, Avram, Alexandra Ioana, Munk, S. & Lopez-Contreras, Andres, Jun 2017, In: Transgenic Research. 26, 3, p. 429-434 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  42. Published

    Antinociceptive effects of voluntarily ingested buprenorphine in the hot-plate test in laboratory rats

    Hestehave, Sara, Munro, G., Brønnum Pedersen, T. & Abelson, Klas, Jun 2017, In: Laboratory Animals. 51, 3, p. 264-272 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  43. Published

    Socially transmitted diffusion of a novel behavior from subordinate chimpanzees

    Watson, S. K., Reamer, L. A., Mareno, M. C., Vale, G., Harrison, R. A., Lambeth, S. P., Schapiro, S. & Whiten, A., Jun 2017, In: American Journal of Primatology. 79, 6, 10 p., e22642.

    Research output: Contribution to journalJournal articleResearchpeer-review

  44. Published

    Lipocalin-2 from both myeloid cells and the epithelium combats Klebsiella pneumoniae lung infection in mice

    Cramer, E. P., Dahl, S. L., Rozell, B., Knudsen, K. J., Thomsen, K., Moser, Claus Ernst, Cowland, J. B. & Borregaard, N., 18 May 2017, In: Blood. 129, 20, p. 2813-2817 5 p.

    Research output: Contribution to journalComment/debateResearch

  45. Published

    Behavioral Management of Pan spp.

    Reamer, L., Haller, R., Lambeth, S. P. & Schapiro, S., 10 May 2017, Handbook of Primate Behavioral Management. Steven J., S. (ed.). 1 ed. Boca Raton: CRC Press, p. 385-408

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearch

  46. Published

    Collaborative Research and Behavioral Management

    Schapiro, S., Brosnan, S. F., Hopkins, W. D., Whiten, A., Kendal, R., Sherwood, C. C. & Lambeth, S. P., 10 May 2017, Handbook of Primate Behavioral Management. Steven J., S. (ed.). 1 ed. Boca Raton: CRC Press, p. 243-254

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearch

  47. Published

    Introduction to the Handbook of Primate Behavioral Management

    Schapiro, S., 10 May 2017, Handbook of Primate Behavioral Management. Steven J., S. (ed.). 1 ed. Boca Raton: CRC Press, p. 3-8

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearch

  48. Published

    Managing a Behavioral Management Program

    Schapiro, S. & Lambeth, S. P., 10 May 2017, Handbook of Primate Behavioral Management. Steven J., S. (ed.). 1 ed. Boca Raton: CRC Press, p. 265-278

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearch

  49. Published

    Rules, Regulations, Guidelines, and Directives

    Hau, Jann & Bayne, K., 10 May 2017, Handbook of Primate Behavioral Management. Steven J., S. (ed.). 1 ed. Boca Raton: CRC Press, p. 25-36

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearch

  50. Published

    Vendor-derived differences in injury-induced pain phenotype and pharmacology of Sprague-Dawley rats: Does it matter?

    Kristensen, P. J., Heegaard, Anne-Marie, Hestehave, Sara, Jeggo, R. D., Bjerrum, Ole Jannik & Munro, G., Apr 2017, In: European Journal of Pain. 21, 4, p. 692-704 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  51. Published

    Etiology of Triarchic Psychopathy Dimensions in Chimpanzees (Pan troglodytes)

    Latzman, R. D., Patrick, C. J., Freeman, H. D., Schapiro, S. J. & Hopkins, W. D., 1 Mar 2017, In: Clinical Psychological Science. 5, 2, p. 341-354 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  52. Published

    A chronic increase of corticosterone age-dependently reduces systemic DNA damage from oxidation in rats

    Jørgensen, Anders, Kalliokoski, Otto, Forsberg, K., Breitenstein, K., Weimann, A., Henriksen, T., Hau, Jann, Wörtwein, Gitta, Poulsen, Henrik Enghusen & Jørgensen, Martin Balslev, Mar 2017, In: Free Radical Biology & Medicine. 104, p. 64-74 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  53. Published

    Exploring the antigenic response to multiplexed immunizations in a chicken model of antibody production

    Kousted, T. M., Kalliokoski, Otto, Christensen, S. K., Winther, Jakob R. & Hau, Jann, Mar 2017, In: Heliyon. 3, 3, 19 p., e00267.

    Research output: Contribution to journalJournal articleResearchpeer-review

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