An overview of animal models in experimental schistosomiasis and refinements in the use of non-human primates

Research output: Contribution to journal › Review › Research › peer-review

Standard

An overview of animal models in experimental schistosomiasis and refinements in the use of non-human primates. / Farah, Idle O.; Kariuki, Thomas M.; King, Christopher L.; Hau, Jann.

In: Laboratory Animals, Vol. 35, No. 3, 2001, p. 205-212.

Research output: Contribution to journal › Review › Research › peer-review

Harvard

Farah, IO, Kariuki, TM, King, CL & Hau, J 2001, 'An overview of animal models in experimental schistosomiasis and refinements in the use of non-human primates', Laboratory Animals, vol. 35, no. 3, pp. 205-212. https://doi.org/10.1258/0023677011911570

APA

Farah, I. O., Kariuki, T. M., King, C. L., & Hau, J. (2001). An overview of animal models in experimental schistosomiasis and refinements in the use of non-human primates. Laboratory Animals, 35(3), 205-212. https://doi.org/10.1258/0023677011911570

Vancouver

Farah IO, Kariuki TM, King CL, Hau J. An overview of animal models in experimental schistosomiasis and refinements in the use of non-human primates. Laboratory Animals. 2001;35(3):205-212. https://doi.org/10.1258/0023677011911570

Author

Farah, Idle O. ; Kariuki, Thomas M. ; King, Christopher L. ; Hau, Jann. / An overview of animal models in experimental schistosomiasis and refinements in the use of non-human primates. In: Laboratory Animals. 2001 ; Vol. 35, No. 3. pp. 205-212.

Bibtex

@article{5953f46a466541d5834de4c6de10b11f,
title = "An overview of animal models in experimental schistosomiasis and refinements in the use of non-human primates",
abstract = "The complex nature of the schistosome parasite and its interaction with the mammalian host necessitates the continued use of live intact animal models in schistosomiasis research. This review acknowledges this necessity and highlights some of the important insights into the pathogenesis of the disease that have been gained from using various animal models. The use of non-human primates as more relevant models of human schistosomiasis is stated. In addition, the importance of animal welfare consideration when using primates for research is emphasized. Finally, some guidelines for the refined capture, handling and early humane end-points for non-human primates to be used in experimental schistosomiasis are suggested.",
keywords = "Animal models, Animal welfare, Humane endpoints, Non-human primates, Refinement, Schistosoma mansoni",
author = "Farah, {Idle O.} and Kariuki, {Thomas M.} and King, {Christopher L.} and Jann Hau",
year = "2001",
doi = "10.1258/0023677011911570",
language = "English",
volume = "35",
pages = "205--212",
journal = "Laboratory Animals",
issn = "0023-6772",
publisher = "SAGE Publications",
number = "3",

}

RIS

TY - JOUR

T1 - An overview of animal models in experimental schistosomiasis and refinements in the use of non-human primates

AU - Farah, Idle O.

AU - Kariuki, Thomas M.

AU - King, Christopher L.

AU - Hau, Jann

PY - 2001

Y1 - 2001

N2 - The complex nature of the schistosome parasite and its interaction with the mammalian host necessitates the continued use of live intact animal models in schistosomiasis research. This review acknowledges this necessity and highlights some of the important insights into the pathogenesis of the disease that have been gained from using various animal models. The use of non-human primates as more relevant models of human schistosomiasis is stated. In addition, the importance of animal welfare consideration when using primates for research is emphasized. Finally, some guidelines for the refined capture, handling and early humane end-points for non-human primates to be used in experimental schistosomiasis are suggested.

AB - The complex nature of the schistosome parasite and its interaction with the mammalian host necessitates the continued use of live intact animal models in schistosomiasis research. This review acknowledges this necessity and highlights some of the important insights into the pathogenesis of the disease that have been gained from using various animal models. The use of non-human primates as more relevant models of human schistosomiasis is stated. In addition, the importance of animal welfare consideration when using primates for research is emphasized. Finally, some guidelines for the refined capture, handling and early humane end-points for non-human primates to be used in experimental schistosomiasis are suggested.

KW - Animal models

KW - Animal welfare

KW - Humane endpoints

KW - Non-human primates

KW - Refinement

KW - Schistosoma mansoni

UR - http://www.scopus.com/inward/record.url?scp=0034961969&partnerID=8YFLogxK

U2 - 10.1258/0023677011911570

DO - 10.1258/0023677011911570

M3 - Review

C2 - 11463066

AN - SCOPUS:0034961969

VL - 35

SP - 205

EP - 212

JO - Laboratory Animals

JF - Laboratory Animals

SN - 0023-6772

IS - 3

ER -

ID: 369371308